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Erase HIV

Enterprise for Research & Advocacy to Stop & Eradicate HIV

Enterprise for Research & Advocacy to Stop & Eradicate HIV 

Led by Drs. Paiardini, Kulpa, and Silvestri, is one of the Martin Delaney Collaboratories (MDC) for HIV Cure Research, the flagship NIH program on HIV cure research, funded to Emory University. 

These leaders and their team members are renowned for their cutting-edge and clinically relevant HIV cure research.

As part of their studies, Paiardini, Kulpa, Silvestri, and their collaborators will define the key features of the immune system needed to control HIV infection and test immune-based therapies with the potential to eliminate or control the virus in the absence of antiretroviral therapy, something that the field has been unable to achieve despite many years of research.

Our common goal is to foster multidisciplinary collaborations and partnerships between academia, industry, government, and community to accelerate the pace of HIV research aimed at developing curative strategies.

We have partnered with an advocacy team who have been leading the fight for HIV education and reproductive justice for over 30 years.

We have assembled a research team of world leaders in T cell biology and HIV pathogenesis who are working at the forefront of HIV cure. 

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SisterLove

SisterLove, the oldest women’s reproductive health and justice organization in the Southeastern U.S., is committed to eradicating the adverse impacts of HIV and reproductive health rights and justice challenges that impact women and their families.

 

They do this through a multi-pronged approach: education, prevention, support, research, and human rights advocacy both in the U.S. and globally. 

Learn More

The Reginald &  Dionne Smith Foundation

Since its inception on September 13, 2012, the Reginald and Dionne Smith Foundation (RDSF) has been dedicated to eradicating stigma and enhancing HIV awareness, specifically addressing the distinct challenges faced by families across the United States impacted by HIV/AIDS, viral hepatitis, and substance use disorders.

The London Patient

Adam Castillejo, formerly known as the 'London Patient', is the second person in the world to be healed from HIV, and one of our community partners. Adam underwent a stem cell transplant to treat lymphoma and his donor carried a mutation that made him resistant to the virus. Learn more about his incredible story on our Community Partners page.

We aim to deliver community supported therapeutics that disrupt the underlying mechanisms of HIV persistence that will result in sustained viral remission and ultimately eradication of the rebound competent viral reservoir.

Our Milestones

Characterization of pro-latency and cytotoxic CD8 T cell functions for successful post-treatment control and latent reservoir eradication of HIV-1.

Characterization of pro-latency and cytotoxic CD8 T cell functions for successful post-treatment control and latent reservoir eradication of HIV-1.

Immune based strategies to induce host immune responses able to intercept and control the rebounding virus

Immune based strategies to induce host immune responses able to intercept and control the rebounding virus

Modulation of CD8+ T cell pro-latency activity to effectively induce “shock and suicide” to eradicate the latent reservoir.

Modulation of CD8+ T cell pro-latency activity to effectively induce “shock and suicide” to eradicate the latent reservoir.

Our Leadership

Mirko Paiardini PhD

Professor, Chief, Division of Microbiology & Immunology, Emory University School of Medicine, Principal investigator (Corresponding)

Deanna Kulpa PhD

Associate Professor, Emory University School of Medicine, Principal Investigator

Guido Silvestri MD

Professor, Executive Associate Dean of Research Strategy, Emory University School of Medicine, Principal Investigator

Joseph Sodroski MD

Professor, Dana-Faber Cancer Institute, Harvard Medical School, ERASE HIV Executive Committee

Mathias Lichterfeld MD, PhD

Professor, Brigham and Women’s Hospital, Harvard Medical School, ERASE HIV Executive Committee

Dazon Dixon Diallo DHL, MPH

Founder and President of SisterLove, ERASE HIV Executive Committee

Asier Sáez-Cirión PhD

Assistant Professor and Team Leader, Institute Pasteur, Paris, France, ERASE HIV Executive Committee

Bonnie Howell PhD

Associate Vice President, Global Head of Quantitative Bioscience & Nonclinical Pharmacology Pharmacology, Merck & Co., Inc.

Drew Weissman MD, PhD

Professor, Penn Medicine, University of Pennsylvania, Noble Prize for Medicine 2024

Micheal Betts PhD

Professor, Perelman School of Medicine University of Pennsylvania

Edward Kreider MD PhD

Instructor in Medicine Penn Measey Scholar in Molecular Medicine University of Pennsylvania

Andrés Finzi PhD

Professor, Université de Montréal, Faculty of Medicine, Montréal, Canada

Scientific Advisory Board

Viviana Simon, M.D., Ph.D.

Icahn SOM at Mount Sinai
Professor

Sarah Palmer, Ph.D.

The Westmead Institute for Medical Research the University of Sydney
Professor

Daniel Douek, M.D., Ph.D.

National Institute of Allergy and Infectious Diseases, NIH
Chief, Human Immunology Section

Frank Kirchhoff, Ph.D.

Ulm University Medical Center,
Professor, Director of Institute of Molecular Virology

Elias Haddad, Ph.D.

Drexel University ​
Professor
M.D,, PhD. Program director

Highlights

Our Events

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Contact us

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AIDS walk photo.HEIC
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In October 19th, 2024, Erase HIV & SisterLove's team participated in the AIDS walk Atlanta

Research

Learn about our latest publications

AIDS Walk

October 19

By Erase HIV and SisterLove

Do you wanna learn more?

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AIDS 2024

The 25th International AIDS Conference | July 22-July 26 in Munich, Germany

"Teaching an Old Dog a New Trick: How to Harness the Immune System to Control HIV." by Mirko Paiardini

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The Martin Delaney Collaboratories

2024 Annual Meeting |November 18-20

NIAID Conference Center, 5601 Fishers Lane, Rockville, MD.

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